Story

 

Edward and Alphonse Elric are brothers living in the village of Resembool in the country of Amestris (アメストリス Amesutorisu?). Their father, Hohenheim, left home when Edward and Alphonse were still very young. Years later, their mother, Trisha Elric, dies of a terminal illness. After their mother's death, Edward becomes determined to bring her back through the use of alchemy, an advanced science in which an object can be reformed into something completely different. They learn of the Human Transmutation, a forbidden art in which one attempts to create a human who had died. However, this attempt failed, ultimately resulting in the loss of Edward's left leg and Alphonse's entire body. In a desperate effort to save his brother, Edward sacrifices his right arm to affix his brother's soul to a suit of armor. After that, Edward's left leg and right arm are fitted with two sets of automail, a type of advanced prosthetic limb, created for him by his close family friends Winry Rockbell and her grandmother Pinako.

Edward sets out to become a State Alchemist (国家錬金術師 Kokka Renkinjutsushi?), which is an alchemist employed by the State Military of Amestris. State Alchemists are identified by their silver pocket watches and the unique titles assigned to them upon becoming a State Alchemist. Becoming a State Alchemist would enable Edward to use the extensive resources available to them to discover a way to restore what he and Alphonse had lost, but it also turns him into a "weapon" of the military, who are famous for destroying almost all Ishval's population in a past Civil War. The brothers eventually learn of the Philosopher's Stone, a legendary stone that is said to allow the holder to completely bypass the law of Equivalent Exchange, and set off in search of it as a means to restore their bodies. Along the way they discover that the Philosopher's Stone requires human lives to create it, and find others who seek it as well, doing almost whatever they can to get their hands on it. They are attacked by the homunculi, a group of human-like creatures that carry pieces of the Philosopher's Stone inside themselves. They are named after the seven deadly sins and act as primary villains in the series.

A man known simply as "Father" is the creator of all the homunculi and commands them from behind the curtains of the High Command of the country Amestris. He was originally a small ball of shadows inside a round flask with the nickname of "homunculus" created with the blood of Hohenheim. He goads a king into performing Human Transmutation, resulting in the destruction of the country Xerxes. As a gift for helping him, Father made Hohenheim immortal by rebuilding his body with half the souls of the population of Xerxes; he used the other half to create a body for himself in the likeness of Hohenheim. It is suspected that Father plans to use Amestris as a gigantic transmutation circle to create a Philosopher's Stone, but the homunculus Envy hints that, although close, this is not the whole truth.

Differences in adaptations

The stories of the manga and anime separate soon after the encounter with the homuculus Greed during the episodes 32–35, and weave vastly different tales. Father does not exist in the anime. His counterpart is a woman called Dante, a former lover of Hohenheim. Centuries ago, the two were masterful alchemists and perfected methods for making the Philosopher's Stone and a form of immortality in which they use others' bodies until they age. Hohenheim eventually fell in love with another and left Dante, taking with him the perfected Philosopher's Stone formula. Although Dante is still able to jump from body to body to cheat death over the centuries, she is able to spend less and less time in each body as it decays faster with each jump, and each jump causes the stone she possesses to lose its power over time. She uses the Homunculi to spur Edward and Alphonse, along with other Alchemists as desperate as they are, into creating another complete Philosopher's Stone for her.

Having heard of Scar's creation of the Philosopher's Stone, Edward saves the people from Lior from being sacrificed during the the creation of the stone, which is infused into Alphonse's metal body, making him the main focus of Dante's efforts ultimately leading to him being kidnapped. During the fights against the homunculi, when Edward is killed by Envy, Alphonse uses the power of the Philosopher's Stone to heal Edward's body and to reattach his soul. After being revived, Edward risks his own life to bring back his brother in exchange. As a result, Edward ends up on the other side of the gate of alchemy, which turns out to be the Earth, while Alphonse recovers his original body. Determined to return with Alphonse, Edward becomes involved in rocketry research in Transylvania, with the intention to use that technology to try and get back to his home world.

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